Reference is made to the stock exchange notice of 29 August 2018 regarding the board of director’s resolution to increase the share capital in Targovax ASA (the “Company”) in connection with the settlement of restricted stock units.
The share capital increase has today been registered with the Norwegian Register of Business Enterprises (Nw. Foretaksregisteret). The Company’s new registered share capital is NOK 5,261,644.80 comprising of 52,616,448 shares, each with a nominal value of NOK 0.10.
For further information, please contact:
Erik Digman Wiklund, CFO
Phone: + 47 413 33 536
This information is subject to the disclosure requirements pursuant to section 5-2 of the Norwegian Securities Trading Act.
Activating the patient’s immune system to fight cancer
Targovax (OSE:TRVX) is a clinical stage immuno-oncology company developing oncolytic viruses to target hard-to-treat solid tumors. Immuno-oncology is currently one of the fastest growing therapeutic fields in medicine.
Targovax’s lead product candidate, ONCOS-102, is a genetically modified oncolytic adenovirus, which has been engineered to selectively infect and replicate in cancer cells. It activates the immune system to generate tumor-specific immune responses. In a phase I monotherapy trial, ONCOS-102 induced both local and systemic innate and adaptive immune activation, with associated clinical benefit. In an ongoing phase I trial, patients who have progressed on anti-PD1 checkpoint inhibitors and treated with ONCOS-102 in combination with Keytruda, demonstrated responses in three of nine patients (33% ORR) including one complete response. ONCOS-102’s lead indication is mesothelioma, where the virus is currently being tested in a randomized phase I/II trial expected to report around new year 2019-20.