During the first quarter of 2016, Targovax identified promising data from an interim survival analysis of a first cohort and conducted an interim DTH immunological response evaluation of a second cohort of a phase I/II combination study of TB01/GM-CSF and gemcitabine(chemotherapy).
The interim analysis in March indicated promising 1-year overall survival data when combining TG01 with gemcitabine as supplementary treatment of patients with pancreatic cancer, while the response evaluation in April showed that the modified and reduced vaccination schedule generates similar 8-week immune responses in patients with pancreatic cancer, as seen in the initial cohort.
Preparation of new combination clinical trials progressed according to plan, and by the end of first quarter, five new studies are in the process of being set up.
“I am satisfied with development in the first quarter. We manage to keep a lean operation while progressing our clinical program according to plan. Our funding situation is satisfactory, as we have funding through 2016 and even into 2017 by adjusting our current operating model”, says CEO Gunnar Gårdemyr.
The quarterly report and presentation are also available at
Today, May 12, 2016 at 14:30 CET (08:30 EST) Targovax will host a telephone conference which will include a presentation of the results, followed by a Q&A session. CEO Gunnar Gårdemyr, CFO Øystein Soug and CMO Magnus Jäderberg will be presenting on the call. Call in details can be found below.
Norway Toll-Free Number: 800 19 747
Norway Toll Number: +472350 0559
UK Toll-Free Number: 08082370030
UK Toll Number: +442031394830
US Toll-Free Number: 1866 928 7517
US Toll Number: +1 718 873 9077
Access code: 14438925#
Please make sure to dial – in at least 5-10 minutes ahead to complete your registration.
See attached list for more dial-in numbers.
For further information, please contact
Gunnar Gårdemyr, CEO
Phone: +41 798 340 585
Øystein Soug, CFO
Phone: +47 906 56 525
Arming the patient’s immune system to fight cancer
Targovax is a clinical stage immuno-oncology company developing targeted immunotherapy treatments for cancer patients. Targovax has a broad and diversified immune therapy portfolio and aims to become a world leader in its area. The company is currently developing two complementary and highly targeted approaches in immuno-oncology.
ONCOS – 102 is a virus-based immunotherapy platform based on engineered oncolytic viruses armed with potent immune-stimulating transgenes targeting solid tumors. This treatment is designed to reactivate the immune system’s capacity to recognize and attack cancer cells.
TG01 and TG02 are part of a peptide-based immunotherapy platform targeting the difficult to treat RAS mutations found in more than 85% of pancreatic cancers, 50% of colorectal cancer and 20-30% of all cancers. Targovax is working towards demonstrating that TG vaccines will prolong time to cancer progression and increase survival.
These product candidates will be developed in combination with multiple treatments, including checkpoint inhibitors in several cancer indications. Targovax also has a number of other cancer immune therapy candidates in the early stages of development.